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RX 6400 vs R9 280

Performance comparison: which is faster?

Radeon RX 6400 (AMD, 2022) and Radeon R9 280 (AMD, 2014) are compared here. Compare scores and VRAM, generative AI usability, and CPUs that pair well with each GPU.

Overall performance: RX 6400 is about 11.1% faster

For generative AI, the higher-VRAM RX 6400(4GB) has the advantage. For gaming, prioritize performance score and CPU compatibility; for AI, prioritize VRAM.

AMD / RX 6000
RX 6400
5,000 pts
VRAM 4GB · 2022
Best Overall Performance
→ RX 6400 Details
AMD / R9
R9 280
4,500 pts
VRAM 3GB · 2014
→ R9 280 Details

Performance Score Comparison

RX 64005,000 pts
R9 2804,500 pts

Relative performance score (higher is faster). Actual fps varies by resolution, game, and CPU configuration.

Specification Comparison

ItemRX 6400R9 280
Performance Score5,0004,500
VRAM4GB3GB
ManufacturerAMDAMD
SeriesRX 6000R9
Release Year20222014
Compatible CPU ExampleAMD A8-7670KAMD FX-4100

Generative AI Models Enabled by the VRAM Difference

These generative AI models can run on only one GPU because of the VRAM difference (Stable Diffusion, Flux, LLMs, and others).

Runs Only on RX 6400 (4GB)

  • Stable Diffusion 1.5
  • SDXL (Q4量子化)
  • Real-ESRGAN x4
  • Gemma 4 E2B (Q4)
  • Qwen3.5 2B (Q4)
  • MiniCPM5 2B (Q4)
  • XTTS v2 (音声複製)
  • RVC (リアルタイム声変換)
  • kotoba-whisper v2.2
  • Qwen3-ASR 0.6B

Runs Only on R9 280 (3GB)

— None (all models that run on RX 6400 also run here)

Which Should You Choose?

If You Want To...Recommended
Prioritize high fps and smooth performance in demanding gamesRX 6400
Run larger generative AI and LLM modelsRX 6400
Prioritize value and adequate performanceR9 280 (the lower model is often sufficient)

Check the Bottleneck with Your CPU →

FAQ

Which is faster, RX 6400 or R9 280?

RX 6400 is about 11.1% higher by score (RX 6400: 5000 points / R9 280: 4500 points). Actual fps also varies by resolution, game, and CPU, so price is a reasonable deciding factor when the gap is only a few percent.

How do generative AI support and VRAM differ between RX 6400 and R9 280?

RX 6400 has 4GB of VRAM, while R9 280 has 3GB; RX 6400 has more. If image generation or a local LLM is even a possibility, the higher-VRAM option provides more room.

Which CPUs pair well with RX 6400 and R9 280?

Using our guideline, AMD A8-7670K pairs well with RX 6400 and AMD FX-4100 with R9 280 (CPU:GPU ≈ 0.9:1). If the CPU is too weak, replacing the GPU may not raise fps, so check the combination before buying.

Related Comparisons and Detail Pages

→ RX 6400 Details / R9 280 Details / Compare Another Combination