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R9 280X vs RX 6400

Performance comparison: which is faster?

Radeon R9 280X (AMD, 2014) and Radeon RX 6400 (AMD, 2022) are compared here. Compare scores and VRAM, generative AI usability, and CPUs that pair well with each GPU.

Overall performance: nearly equal

For generative AI, the higher-VRAM RX 6400(4GB) has the advantage. For gaming, prioritize performance score and CPU compatibility; for AI, prioritize VRAM.

AMD / R9
R9 280X
5,000 pts
VRAM 3GB · 2014
→ R9 280X Details
AMD / RX 6000
RX 6400
5,000 pts
VRAM 4GB · 2022
→ RX 6400 Details

Performance Score Comparison

R9 280X5,000 pts
RX 64005,000 pts

Relative performance score (higher is faster). Actual fps varies by resolution, game, and CPU configuration.

Specification Comparison

ItemR9 280XRX 6400
Performance Score5,0005,000
VRAM3GB4GB
ManufacturerAMDAMD
SeriesR9RX 6000
Release Year20142022
Compatible CPU ExampleAMD A8-7670KAMD A8-7670K

Generative AI Models Enabled by the VRAM Difference

These generative AI models can run on only one GPU because of the VRAM difference (Stable Diffusion, Flux, LLMs, and others).

Runs Only on R9 280X (3GB)

— None (all models that run on RX 6400 also run here)

Runs Only on RX 6400 (4GB)

  • Stable Diffusion 1.5
  • SDXL (Q4量子化)
  • Real-ESRGAN x4
  • Gemma 4 E2B (Q4)
  • Qwen3.5 2B (Q4)
  • MiniCPM5 2B (Q4)
  • XTTS v2 (音声複製)
  • RVC (リアルタイム声変換)
  • kotoba-whisper v2.2
  • Qwen3-ASR 0.6B

Which Should You Choose?

If You Want To...Recommended
Prioritize high fps and smooth performance in demanding gamesR9 280X
Run larger generative AI and LLM modelsRX 6400
Prioritize value and adequate performanceR9 280X (the lower model is often sufficient)

Check the Bottleneck with Your CPU →

FAQ

Which is faster, R9 280X or RX 6400?

Their scores are nearly identical (R9 280X: 5000 points / RX 6400: 5000 points). In this case, compare price, VRAM, and power draw.

How do generative AI support and VRAM differ between R9 280X and RX 6400?

R9 280X has 3GB of VRAM, while RX 6400 has 4GB; RX 6400 has more. If image generation or a local LLM is even a possibility, the higher-VRAM option provides more room.

Which CPUs pair well with R9 280X and RX 6400?

Using our guideline, AMD A8-7670K pairs well with R9 280X and AMD A8-7670K with RX 6400 (CPU:GPU ≈ 0.9:1). If the CPU is too weak, replacing the GPU may not raise fps, so check the combination before buying.

Related Comparisons and Detail Pages

→ R9 280X Details / RX 6400 Details / Compare Another Combination