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RX 7900 GRE vs Instinct MI100

Performance comparison: which is faster?

Radeon RX 7900 GRE (AMD, 2024) and AMD Instinct MI100 (AMD, 2020) are compared here. Compare scores and VRAM, generative AI usability, and CPUs that pair well with each GPU.

Overall performance: RX 7900 GRE is about 14% faster

For generative AI, the higher-VRAM Instinct MI100(32GB) has the advantage. For gaming, prioritize performance score and CPU compatibility; for AI, prioritize VRAM.

AMD / RX 7000
RX 7900 GRE
28,500 pts
VRAM 16GB · 2024
Best Overall Performance
→ RX 7900 GRE Details
AMD / Instinct
Instinct MI100
25,000 pts
VRAM 32GB · 2020
→ Instinct MI100 Details

Performance Score Comparison

RX 7900 GRE28,500 pts
Instinct MI10025,000 pts

Relative performance score (higher is faster). Actual fps varies by resolution, game, and CPU configuration.

Specification Comparison

ItemRX 7900 GREInstinct MI100
Performance Score28,50025,000
VRAM16GB32GB
ManufacturerAMDAMD
SeriesRX 7000Instinct
Release Year20242020
Compatible CPU ExampleRyzen 9 7950X3DCore Ultra 7 165H

Generative AI Models Enabled by the VRAM Difference

These generative AI models can run on only one GPU because of the VRAM difference (Stable Diffusion, Flux, LLMs, and others).

Runs Only on RX 7900 GRE (16GB)

— None (all models that run on Instinct MI100 also run here)

Runs Only on Instinct MI100 (32GB)

  • FLUX.2 [klein] 9B (FP8)
  • Qwen-Image (FP8)
  • FLUX.2 [dev] (GGUF Q4)
  • FLUX.2 [dev] (GGUF Q5)
  • Qwen-Image (GGUF Q8)
  • CogVideoX-5B
  • Wan 2.2 A14B (FP8)
  • Qwen 2.5 32B (Q4)
  • Llama 3.3 70B (Q2)
  • Mixtral 8x7B (Q4)

Which Should You Choose?

If You Want To...Recommended
Prioritize high fps and smooth performance in demanding gamesRX 7900 GRE
Run larger generative AI and LLM modelsInstinct MI100
Prioritize value and adequate performanceInstinct MI100 (the lower model is often sufficient)

Check the Bottleneck with Your CPU →

FAQ

Which is faster, RX 7900 GRE or Instinct MI100?

RX 7900 GRE is about 14% higher by score (RX 7900 GRE: 28500 points / Instinct MI100: 25000 points). Actual fps also varies by resolution, game, and CPU, so price is a reasonable deciding factor when the gap is only a few percent.

How do generative AI support and VRAM differ between RX 7900 GRE and Instinct MI100?

RX 7900 GRE has 16GB of VRAM, while Instinct MI100 has 32GB; Instinct MI100 has more. If image generation or a local LLM is even a possibility, the higher-VRAM option provides more room.

Which CPUs pair well with RX 7900 GRE and Instinct MI100?

Using our guideline, Ryzen 9 7950X3D pairs well with RX 7900 GRE and Core Ultra 7 165H with Instinct MI100 (CPU:GPU ≈ 0.9:1). If the CPU is too weak, replacing the GPU may not raise fps, so check the combination before buying.

Related Comparisons and Detail Pages

→ RX 7900 GRE Details / Instinct MI100 Details / Compare Another Combination